药物综合治疗肝硬化合并上消化道出血的临床体会.docVIP

药物综合治疗肝硬化合并上消化道出血的临床体会 　　doi：10.3969/j.issn.1007-614x.2014.14.17 　　摘 要 目的：观察药物综合治疗肝硬化合并上消化道出血的临床效果。方法：2009年8月-2013年10月收治肝硬化合并上消化道出血患者30例，随机分为对照组和研究组，对照组患者给予常规治疗，研究组患者在此基础上给予药物综合治疗，对比观察两组患者止血时间、便血时间、治疗效果及不良反应。结果：研究组治疗总有效率93.3%显著高于对照组的53.3%，不良反应发生率20.0%显著低于对照组的53.3%，止血时间和便血时间明显短于对照组，对比差异具有统计学意义（P0.05）。结论：药物综合治疗肝硬化合并上消化道出血能显著降低不良反应发生率，效果好，值得大力推广应用。 　　关键词 肝硬化 上消化道出血 药物综合治疗 止血 便血 　　Clinical experience of medicine comprehensive treatment in liver cirrhosis combined with upper gastrointestinal hemorrhage 　　Gu Xuexiu 　　The internal medicine department of the peoples hospital in Xingren County，Guizhou Province，562300 　　Abstract Objective：To observe the clinical effect of medicine comprehensive treatment in liver cirrhosis combined with upper gastrointestinal hemorrhage.Methods：30 cases of patients with liver cirrhosis combined with upper gastrointestinal hemorrhage were admitted from September 2009 to October 2013.They were randomly divided into the control group and the study group.Patients in the control group were given routine treatment，while patients in study group were given medicine comprehensive treatment on this basis.The hemostatic time，hematochezia time，therapeutic effect and adverse reaction of patients in two groups were compared and observed.Results：The treatment total effective rate 93.3% in the study group was significantly higher than 53.3% of the control group.The incidence rate of adverse reaction of 20% was significantly lower than 53.3% of the control group.The hemostatic time and hematochezia time were shorter than that of the control group with statistically significant differences（P0.05）.Conclusion：The medicine comprehensive treatment in liver cirrhosis combined with upper gastrointestinal hemorrhage can significantly reduce the incidence rate of adverse reactions，and it has good effect，so it is worth to popularize application. 　　Key words Liver cirrhosis；Upper gastrointestinal hemorrhage；Medicine comprehensive treatment；Hemostasis；Hematoc