Principles of Epidemiology CORE 5520 (32832 - 匹.pptVIP

Bias, Confounding and the Role of Chance Principles of Epidemiology Lecture 5 Dona Schneider, PhD, MPH, FACE To Show Cause We Use Koch’s Postulates for Infectious Disease Hill’s Postulates for Chronic Disease and Complex Questions Strength of Association – Tonight’s entire lecture Biologic Credibility Specificity Consistency with Other Associations Time Sequence Dose-Response Relationship Analogy Experiment Coherence To Show a Valid Statistical Association We need to assess: Bias: whether systematic error has been built into the study design Confounding: whether an extraneous factor is relat