ANCA相关性血管炎课件.pptVIP

ANCA相关性血管炎的诊治 安徽医科大学第一附院风湿免疫科 徐胜前 Classification the Chapel Hill Consensus Conference of 1994 Large-vessel vasculitides (2) Medium-vessel vasculitides (2) Small-vessel vasculitides (many) ANCA-associated (5) Non-ANCA-associated (many) Large Vessel Vasculitides (2) Takayasu’s arteritis Giant cell arteritis Medium Vessel Vasculitides (3) Polyarteritis nodosa (PAN) Kawasaki’s disease = Mucocutaneous LN syndrome Polyarteritis Nodosa (PAN) 40-60岁, 男性略多. 累及中等血管也可以累及小血管. 体重减轻, 皮肤损害 (紫癜, 青斑或网青斑, 溃疡, 结节), 多发性单神经炎, 腹痛, 睾丸痛, 高血压, 关节痛/肌痛 HBV感染 肾损害 MRA: 动脉瘤和血管狭窄 预后: 5年存活率: 13%(未治疗),40%(治疗后) Polyar