病毒的遗传与变异.pptVIP

Viral Genetics and Variation病毒的遗传与变异 Conceptions Genetics遗传: After virus replicates , the characters on the progeny virus are similar with the previous generation. Variation变异: After virus replicates , the characters on the progeny virus are different with the previous generation. 一、 Variation mechanism 病毒变异的机制 Heritable variation遗传型变异 因病毒遗传物质核酸发生了改变，导致其变异后的性状可遗传给子代病毒。 Non- Heritable variation非遗传型变异 又称基因产物的相互作用，因病毒核酸并未发生改变，所以此变异一般不能遗传。 （一） Heritable variation 遗传型变异 Virulence changes ※ Conditional lethal mutant