2011年Pharmacology.ppt

Pharmacology  What is pharmacology? The word pharmacology derives from the Greek word for drug, pharmakon. Pharmacology is the medical science that studies the nature and the properties of drugs, as well as the interactions between drugs and the body Pharmacodynamics Effect, Mechanism Absorption, Distribution, Metabolism, Elimination Pharmacokinetics DRUG-BODY INTERACTIONS Pharmacodynamics (pharmacodynamic processes) to study the biochemical and physiological effects mechanisms of action Drug grouped to treat a particular symptom or disease Drug group Central nervous system drugs Cardiovascular drugs Respiratory drugs Gastrointestinal drugs Antimicrobial drugs（抗菌药） Pharmacokinetics(pharmacokinetic processes) To govern the absorption, distribution, metabolism and elimination of drugs Drug A drug is a chemical substance that can modulate the current physiological status of a biological system. is defined as a chemical which is utilized for the diagnosis, prevention and cure of an unwanted health condition (definition by FDA) Basic knowledge of drug DRUG NOMENCLATURE DRUG PREPARATIONS DRUG ADMINISTRATION Drug nomenclature Chemical name Generic name（属名） Brand name（品名） Brand name sometimes is more popular than generic name 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo [4,3-d] pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl piperazine / Sildenafil / Viagra (1-[[3-(6,7-二氢-1-甲基-7-氧-3-丙基-1H-吡唑并-[4,3-d]嘧啶-5-基)-4-乙氧苯基]璜酰基]-4-甲基哌嗪) Acetylsalicylic acid / aspirin / Bayer乙酰水杨酸 Preparations suspension tablet capsule ointment solution aerosol Drug administration Oral Inhalational Topical（局部） instillation Suppository Parenteral administration intradermal injection subcutaneous injection intravenous injection Intramuscular injection The effects of drugs Therapeutic action of drugs Excitation : diuretics Inhibition : asprin(NSAIDs) non-steroidal anti-inflammatory durgs 非类固醇抗炎药 Etiological treatment