Hyperbilirubinemia Oregon Health Science 高胆红素血症俄勒冈健康amp科学.pptVIP

Hyperbilirubinemia Case 1 5 day old former term male infant born to a 23 y.o. G1P0-1 woman. Is exclusively breastfeeding. Has total bilirubin of 25, direct is 0.7. Both mother and baby are O+, and coombs is negative. Phototherapy is started and baby is fed, 6 hours later the total bilirubin level is 19. Breastfeeding consult is done. Physiologic Hyperbilirubinemia Increased production Short RBC lifespan Increased shunt bilirubin Decrease clearance Portal vein shunting via ductus venosus Decreased conjugation Decreased UDPGA synthesis Decreased UDPG transferase Increased enterohepatic ci