III三. LES TEMPS DE DEMIVIE physiologie.envt.fr.pptVIP

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III三. LES TEMPS DE DEMIVIE physiologie.envt.fr.ppt

III三. LES TEMPS DE DEMIVIE physiologie.envt.fr

The half-life The plasma half-life Synonymous half-life of elimination half-life of the terminal phase The half-life Half-life has the apparent advantage of being a familiar term The half-life Definition Time required to divide the plasma concentration by two after reaching pseudo-equilibrium distribution Not the time necessary for the amount of administered drug in the body to fall by one-half The half-life Meaning in terms of drug elimination (half-life vs mean residence time (MRT)) The half-life Meaning in terms of drug elimination Pharmacokinetic meaning of half-life Half-life vs. Clearan

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