Kein Folientitel Alexander Haslberger没有folientitel haslberger 亚历山大.pptVIP

Microbial stimuli that promote DC maturation Bacteria ( E. coli, M. tuberculosis, Staph. aureus, Strept. ,... Protozoa LPS Bacterial DNA, Viral and doubled-stranded RNA Bacterial heat shock proteins Migration Exit of activated DCs from peripheral sites Entry into the T cell areas of secondary lymphoid tissues Antigen presentation Upregulation of antigen presenting molecules (MHC class I and class II, CD1) Delivery of antigen to the MHC class I pathway Upregulation of molecules involved in interaction with T lymphocytes Costimulatory molecules (B7-1, B7-2) Adhesion mole