不同程度近视眼的多焦视网膜电图分析.docVIP

不同程度近视眼的多焦视网膜电图分析 　　[摘要]目的 探究不同程度近视眼与正常人多焦视网膜电图的区别。方法 选择2013年1月～2015年12月在我院眼科行多焦视网膜电图检查的135例（255眼）受检者为研究对象，将其分为正常组22例（44眼）、轻度近视组39例（78眼）、中度近视组31例（62眼）、高度近视组28例（56眼）、高度近视伴对侧眼视网膜脱离15例（15眼），对5组行多焦视网膜电图检查。记录并比较5组一阶反应各环形视网膜区域反应密度和P1波的潜伏时间、振幅以及3D图显示模式所表现的整个视网膜的反应密度。结果 5组一阶反应各环形视网膜区域反应密度及P1波的振幅比较，差异有统计学意义（P0.05），在第1环，随着近视程度的增加，逐渐增长；高度近视伴对侧视网膜脱离组与高度近视组比较，差异有统计学意义（P0.05）。5组整个视网膜的反应密度比较，差异有统计学意义（P0.05），近视程度与整个视网膜的反应密度呈负相关（r=-0.507，P=0.011）。结论 采用多焦视网膜电图动态监测近视眼患者视网膜功能，有助于发现、评估其隐匿性眼底改变，帮助判断其预后和转归。 　　[关键词]近视眼；多焦视网膜电图；近视程度；视网膜功能；相关性 　　[中图分类号] R778.1+1 [文献标识码] A [文章编号] 1674-4721（2016）10（c）-0096-04 　　[Abstract]Objective To explore the difference of multifocal electroretinogram between different degree of myopia and normal subjects.Methods 135 cases （255 eyes） given multifocal electroretinogram examination in our hospital from January 2013 to December 2015 were selected as study object and they were divided into 22 cases with 44 eyes in normal group，39 cases with 78 eyes in mild myopia group，31 cases with 62 eyes in moderate myopia group，28 cases with 56 eyes in high myopia group and 15 cases with 15 eyes in high myopia with contralateral retinal detachment group were examined by multifocal electroretinogram.The reaction density of each annular region in retinal during the first order reaction，latent time and amplitude of P1 wave，and the 3D model of the whole reaction density of retina among 5 groups was compared respectively.Results There were significant differencein the reaction density of each annular region in retinal during the first order reaction，and amplitude of P1 wave among 5 groups （P0.05） in the second to sixth ring.In the first ring，with the increasing of the degree of myopia，the latent time of P1 increased.There were significant differences between the high myopia with contralateral retinal detachment group and the high myopia group （P 　　[Key words]Myopia；Multifocal electroretinogram；Degrees of myopia；Retinal function；Correlation 　　近视眼是由于用眼距离过近、时间过长等用眼不当或者遗传、