reviewerscomments.docVIP

  1. 1、本文档共6页,可阅读全部内容。
  2. 2、原创力文档(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
  3. 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载
  4. 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
  5. 5、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
  6. 6、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们
  7. 7、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
  8. 8、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
reviewerscomments

Reviewers’ Comments: Reviewer B: This is a fairly straightforward article written to assess the geometric accuracy of positioning the point A during 2D brachytherapy planning. The authors are using 2D planning via two orthogonal films acquired after brachytherapy catheters were inserted to the patient and they determine the location of the left and right point A on the films via their institutional policy which matches international standard. Then they argue that in some cases, namely when tandem flange is relatively distant from the simulators isocenter in the AP /PA direction or when the tandem’s projection onto the horizontal plane makes a substantial angle with the gantry rotation axis, the corresponding actual position of these points in the patient body deviates from the presumed(defined and needed) position of point As. The researchers quantified this mismatch and parameterized it as a function of the distance of the flange from the simulator’s isocenter in the vertical direction as well as of the angle between the tandem’s projection into the horizontal plane and the gantry rotation axis. Please find my comments: Comment 1: Authors never discussed what type of brachytherapy procedures they are doing, i.e. single fraction CS137 LDR, fractionated HDR etc. This is important to be mentioned, so the reader will have a better picture of the significance of their findings. For example, in fractionated approach, the interfractional variations in implant geometry will smear out potential clinical dosimetric implications of the A point shifts the authors found. In single fraction, long implants, intrafraction applicator motion also smears out potential dosimetric implications. So ma comment is to ask the authors to elaborate on why they think this is clinically relevant. Response: Thank you for your suggestion. The type of brachytherapy procedure we performed was added in the first paragraph of Materials and Methods (Line 352-353). Due to only five or six trea

文档评论(0)

jvdodnnv002 + 关注
实名认证
文档贡献者

该用户很懒,什么也没介绍

1亿VIP精品文档

相关文档