theeffectsofxiangdanzhusheye(compounddanshen.docVIP

The Effects of Xiangdan Zhusheye(Compound Danshen Zhusheye) on Clotting Time of Rabbits SHAO Juan ZHENG Bin CHEN Huiqing LI Tao LIANG Haibin Class 2,Grade 2000,Department of Clinic Medicine Sun Yat-sen University,Guangzhou 510089,P.R.China Tutor:WANG Tinghuai Department of Physiology Sun Yat-sen University,Guangzhou 510089,P.R. China ［Abstract］　Objective This research tries to observe the influence of Xiangdan Zhusheye on the clotting time of rabbits. Methods After ejecting rabbits with the Xiangdan Zhusheye , observe the effect on rabbits and compare the experiment models with contrasts. Results Clotting time of each experiment models has been prolonged in general.The experiment models are different from those of blank models.There are no evident difference among experiment models. Conclusions The Xiangdan Zhusheye can clearly prolong the clotting time of rabbits.In these experiments,the concentration doesn’t clearly influence the effects. ［Key Words］ Xiangdan Zhusheye ; Danshen Root ; Rosewood ;Clotting time 1 Preface Xiangdan Zhusheye is greatly useful in clinical field. It mainly cures ecchymosis angina、myocardial infarction etc. It involved root and rosewood. Danshen root can reduce the degree of mucilaginous obviously. It has the function of inhibiting the concreting of blood, inhibiting the function of blood platelet ,advancing the function of fibrin clotting protein and inhibiting the synthesis of thrombus out of body. Rosewood has the function of inhibiting the synthesis of thrombus out of body. It can obviously inhibit the synthesis of thrombus in experiment. We tried to identify the efficiency of antithrombus of Xiangdan Zhusheye. By observing effect of different dose of Xiangdan Zhusheye on clotting time of rabbits. It can be used as a new exploration of clinical use of Xiangdan Zhusheye.2 2 Materials and methods 2.1 Materials object：9 rabbits (about 1.5kg each, 8 rabbits for formal experiment, 1 for pre-experiment) drug：60 Xiangd