FTICRMS原理及应用郭寅龙中国科学院上海有机化学研究所上海.doc

FTICRMS原理及应用 郭寅龙 中国科学院上海有机化学研究所 上海质谱中心 第一部分：FTICRMS原理 Fourier Transform Ion Cyclotron Resonance Mass Spectrometry 傅立叶变换离子回旋共振质谱 一、仪器结构 Schematic of External Ion Source FTMS with ESI Source Cylindrical Ion Cyclotron Resonance Cell  (ICR Cell, ICR Trap) Basic Features of FTMS Instrumentation 二、基本原理 Basic Principles: Ion Cyclotron Motion Principles of Fourier Transform Mass Spectrometry Cyclotron Motion For a stable circular orbit the centrifugal force outward exactly balances the magnetic force inward. Theory : Detection Excitation and Detection Principles of Fourier Transform Mass S