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Determination of pressure data from velocity data with a view towards its application in cardiovascular mechanics. Part 2 A study of aortic valve stenosis.pdf
International Journal of Engineering Science 113 (2017) 37–50
Contents lists available at ScienceDirect
International Journal of Engineering Science
journal homepage: /locate/ijengsci
Determination of pressure data from velocity data with a view towards its application in cardiovascular mechanics. Part 2: A study of aortic valve stenosis
H. ?vihlová a,?, J. Hron a, J. Málek a, K.R. Rajagopal b, K. Rajagopal c
a Charles University, Faculty of Mathematics and Physics, Mathematical Institute, Sokolovská 83, 186 75 Prague, Czech Republic b Texas AM University, Department of Mechanical Engineering, College Station, TX 77843-3132, United States c University of Texas-Houston/Memorial Hermann Texas Medical Center, Center for Advanced Heart Failure, 6411 Fannin, Houston, TX 77030, United States
article info
Article history: Received 4 January 2017 Accepted 12 January 2017 Available online 26 January 2017
Keywords: Dissipation Heart valve Stenosis Navier–Stokes equation Blood vessel
abstract
This paper is Part 2 of a study of blood ?ow across cardiovascular stenoses. In Part 1, we developed a rigorous mathematical approach for deriving a pressure ?eld from experimental data for a velocity ?eld that can be obtained by direct measurement. In this Part, existing methods for quantifying stenoses, with speci?c reference to cardiac valves, are reviewed. Using the mathematically rigorous and physically accurate approach that we developed in Part 1, for a pre-speci?ed ?ow velocity ?eld proximal to the stenosis and pressure waveform ?eld distal to the stenosis, we ascertain the intro-stenosis and distal ?ow velocity ?eld, pressure ?eld proximal and within the stenosis, and energy dissipation, all as function of position and time. The computed dissipation, kinetic energy and pressure are then presented in an idealized geometry, but with realistic geometry, with a symmetric stenosis.
? 2017 Elsevier Ltd. All rights reserved.
1. Introduction
Stenotic cardiac valve and arterial occlusive
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