食道癌病例对照论文(2).docVIP

盐城市35岁以上居民食道癌发病 影响因素的条件 Logistic回归分析 王学高1，刘爱民2，刘荣海3，赵建华4，戴曙光5，梅茂东6，孙海波7，邱民8 （1.江苏省阜宁县疾病预防控制中心，江苏 阜宁 224400；2. 江苏省大丰市疾病预防控制中心，江苏 大丰 224100；3. 江苏省盐城市疾病预防控制中心，江苏 盐城 224000；4. 江苏省东台市疾病预防控制中心，江苏 东台 224200；5. 江苏省射阳县疾病预防控制中心，江苏 射阳 224300；6. 江苏省滨海县疾病预防控制中心，江苏 滨海 224500；7. 江苏省响水县疾病预防控制中心，江苏 响水 224600；8. 江苏省盐城市盐都区疾病预防控制中心，江苏 盐城 224000） 摘要：[目的] 为了研究我地区食道癌高发的原因，为制定恶性肿瘤高发地区胃癌的相关防治措施提供依据。[方法]以2000年盐城市6县（市、区）35岁以上居民慢性非传染病基线调查中查出的244例胃癌病例为病例组，以1︰5配对从调查对象中选择1220名非胃癌调查对象为对照组，进行胃癌发病影响因素的单因素和多因素条件Logistic回归分析。[结果]32个因素中，肿瘤家族史、戒烟史、常喝绿茶、经常活动、超重、常吃奶及奶奶制品、文化程度较高、睡眠好、口味偏咸、常吃水果、偏辣口味单因素分析有显著意义(P0.05)，其OR值分别为2.55、4.36、0.48、0.38、0.29、2.50、0.53、0.65、0.70、1.43、0.68；进入多因素条件Logistic的因素有肿瘤家族史、戒烟史、常喝绿茶、经常活动、超重、常吃奶及奶奶制品、文化程度较高、睡眠好、常吃水果，OR值分别为2.73、4.40、0.46、0.42、0.28、2.85、0.50、0.70、1.59。[结论]有戒烟史、肿瘤家族史是食道癌发病的危险因素，经常活动、睡眠好、文化程度较高、超重、常喝绿茶是食道癌发病的保护性因素。 Conditional logistic analysis of oesophageal cancer for resident older than 35 in seven county belong to Yancheng city Wang Xuegao, Liu Aiming, Liu Ronghai, etc.Funing Center for Disease Control and Prevention, Funing , 224400 , JiangSu, China. Abstract Object To explore the influencing factor of Oesophageal cancer. Methods A total of 244 diagnosed cases with oesophageal cancer were selected from basic trials investigation for chronic Noninfection Diseases in six county belong to Yancheng city,5 health people matched by sex, age and resident town were selected for every case. Odds ration (OR) and its 95% confidence (CI) for multivariate analysis and univariate analysis were estimated by conditional logistic model analysis. Results Univariate analysis for 32 factor showed that oesophageal cancer was closely relate to eleven factors: history for giving up smoking, family history for tumor,greentea, overweight, activity, good sleep, good education, enough fruit,high salt,milk, being fond of capsicum, OR: 4.36,2.55,0.48,0.29,0.38,0.65,0.53,1.43,0.70,2.50,0.68.Nine factors were selected in multivariate analysis: history for giving up smoking,