某三甲醫院2011年手术科室抗菌药物应用情况分析.docVIP

某三甲医院2011年抗菌药物应用情况分析△ 徐芸1 *，秦侃2，徐丙发2，李磊2，沈娟2，陈瑞3，范鲁雁1，2 # （1.安徽医科大学药学院，合肥市，230032；2. 安徽医科大学第三附属医院，合肥市第一人民医院药学部； 3.安徽中医学院药学院） 摘 要 目的：对某三甲医院2011年抗菌药物的应用情况进行统计，分析抗菌药物使用的特点和趋势，为临床合理用药和科学管理抗菌药物提供依据。方法：收集该院2011年抗菌药物使用资料，对用药金额、用药频度、DDDs、用药强度等进行分析。结果：该院住院患者抗菌药物使用率为65.56％，抗菌药物使用强度达到每百人天60.72DDDs。结论：该院住院患者抗菌药物使用率和使用强度，某些科室存在滥用抗菌药物的现象，进一步规范抗菌药物的应用，使用药更加安全、有效、经济关键词 抗菌药物；金额；用药频度；使用强度 Analysis on use of Antibacterials in urgical department in a 3A-Grade Hospital in 2011 XU Yun1*, QIN Kan2, XU Bing-fa2, LI Lei2, SHEN Juan2, CHEN Rui3, FAN Lu-yan1，2# ABSTRACT OBJRCTIVETo investigate the feature and tendency of the utilization of antibacterials in the hospital in 2011 so as to provide references for the rational use and scientific management of antibacterials. METHODS: The consumption data of the antibacterials in the hospital in 2011 were collected for analysis of consumption sum, drug frequency, DDDs and antibacterial use density (AUD) et al. RESULTS: The usage of antibiotics in our hospital reached 65.56％, the AUD of antibiotics in our hospital reached 60.72DDDsSurgical department of antibiotics usage is 78.96%, higher than Non-surgical department’s 47.89%. COMCLUSIONS: The usage of antibiotics and the AUD in the inpatients of the hospital Higher than required by the Ministry of health in 60% and 40DDDs, there are still some departments which have the abuse of antibacterials, Surgical department accounted for 9 in the usage of antibiotics sorted before the10, in order to further standardize the application of antibacterials, ensure safe, efficient, economical drug use, next the focus of regulation can be put in surgical department. KEY WORDS Antibacterials; Percentage of consumption sum; DDDs; AUD 抗菌药物是临床用药中应用范围最广、品种最多、消耗量最大的一类药物，包括抗生素类、合成抗菌药、抗真菌药等[1]。目前，药物的选择不当、选用的药物剂量、给药频率和用药时间不适当；输注的速度不当；选择的溶媒不当等等[2]。不恰当的抗菌治疗，不仅使感染患者用药疗程和住院时间延长，病死率和耐药性增加，费用加大，还可导致治疗失败和死亡，同时，临床既使选择了药敏报告中抗菌药物，但仍有患者不能获得满意的疗效。笔者《抗菌药物临床应用指导原则》和《2011年全国抗菌药物临床应用专项整治活动方案》对该院2011年抗菌药物应用情况进行，分析抗菌药物使用的特点和趋势，旨在