IARC致癌物.docVIP

IARC对致癌物的最新评价结果 Overall Evaluations of Carcinogenicity to Humans ? Group 1: Carcinogenic to humans (100) ? Agents and groups of agents 4-Aminobiphenyl [92-67-1] (Vol. 1, Suppl. 7; 1987) Arsenic [7440-38-2] and arsenic compounds (Vol. 23, Suppl. 7; 1987) (NB: This evaluation applies to the group of compounds as a whole and not necessarily to all individual compounds within the group) Asbestos [1332-21-4] (Vol. 14, Suppl. 7; 1987) Azathioprine [446-86-6] (Vol. 26, Suppl. 7; 1987) Benzene [71-43-2] (Vol. 29, Suppl. 7; 1987) Benzidine [92-87-5] (Vol. 29, Suppl. 7; 1987) Benzo[a]pyrene [50-32-8] (Vol. 32, Suppl. 7, Vol. 92; in preparation)(NB: Overall evaluation upgraded from 2B to 1 based on mechanistic and other relevant data) Beryllium [7440-41-7] and beryllium compounds (Vol. 58; 1993) N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornaphazine) [494-03-1] (Vol. 4, Suppl. 7; 1987) Bis(chloromethyl)ether [542-88-1] and chloromethyl methyl ether [107-30-2] (technical-grade)(Vol. 4, Suppl. 7; 1987) 1,4-Butanediol dimethanesulfonate (Busulphan; Myleran) [55-98-1] (Vol. 4, Suppl. 7; 1987) Cadmium [7440-43-9] and cadmium compounds (Vol. 58; 1993) Chlorambucil [305-03-3] (Vol. 26, Suppl. 7; 1987) 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU; Semustine) [13909-09-6] (Suppl. 7; 1987) Chromium[VI] (Vol. 49; 1990) Ciclosporin [79217-60-0] (Vol. 50; 1990) Cyclophosphamide [50-18-0] [6055-19-2] (Vol. 26, Suppl. 7; 1987) Diethylstilboestrol [56-53-1] (Vol. 21, Suppl. 7; 1987) Epstein-Barr virus (Vol. 70; 1997) Erionite [66733-21-9] (Vol. 42, Suppl. 7; 1987) Estrogen-progestogen menopausal therapy (combined) (Vol. 72, Vol. 91; in preparation) Estrogen-progestogen oral contraceptives (combined) (Vol. 72, Vol. 91; in preparation)(NB: There is also convincing evidence in humans that these agents confer a protective effect against cancer in the endometrium and ovary) Estrogens, nonsteroidal (Suppl. 7; 1987) (NB: This evaluation applies to the group of compo