ANewNonparametricBayesianModelforGenetic.pptVIP

A New Nonparametric Bayesian Model for Genetic Recombination in Open Ancestral Space ;Outline;Allele: a viable DNA coding on a chromosome – observation Locus : the location of an allele – index of an observation Haplotype: a sequence of alleles – data sequence Recombination: exchange pieces of paired chromosome – state-transition Mutation: any change to a haplotype during inheritance – emission;Terminology and Introduction (2);Terminology and Introduction (3);DP Mixtures for Non-recombination Inheritance (1);DP Mixtures for Non-recombination Inheritance (2);DP Mixtures for Non-recombination Inheritance (3);HMDP for Recombination (1);Each row of the transition matrix in HMM is a DP. Also these DPs are linked by the top level master DP, and have the same set of target states. The mixing proportions for each lower level DP are denoted as , then the jth row of the transition matrix is .;HMDP for Recombination (3);HMDP for Recombination (4);HMDP for Recombination (5);HMDP for Recombination (6);HMDP for Recombination (7);Results (1);Results (2);Results (3);Results (4);Results (5);Results (6);Conclusions