北京科技大学化学专业核酸习题(含答案).docVIP

What can we learn from the double helix structure of DNA? The two strands run in opposite directions; they are antiparallel. Two right-handed, helical. In an aqueous environment, the polar, charged, covalent backbone of alternating deoxyribose and phosphate groups is on the outside of the helix, where interaction with H2O is likely; the hydrophobic purine and pyrimidine bases avoid water by turning toward the inside of the structure. The double helix is stabilized by two types of forces: a. Hydrogen bonds between pairs of complementary bases on opposite strands (A-T;G-C). b. Van der Wa