从临床治疗角度理解2013版+WHO+骨与软组织肿瘤新分类.pdfVIP

中国骨与关节杂志 2015 年 1 月第 4 卷第 1 期 Chinese Journal of Bone and Joint, January 2015, Vol 4, No.1 . 35 . . 指南解读 Intensive reading of guidelines . 从临床治疗角度理解 2013 版 WHO 骨与软组织肿瘤新分类 李南 　韦兴 DOI: 10.3969/j.issn.2095-252X.2015.01.009　　中图分类号：R738.6, R738.1 作者单位：100048 北京，解放军总医院第一附属医院骨肿瘤科、全军骨科研究所 通信作者：韦兴，Email: wxing304@ Understanding of WHO classification of tumors of soft tissue and bone ( 2013 ) from clinical treatment aspects LI Nan, WEI Xing. Orthopedic Institute of CPLA, the first Affiliated Hospital of the General Hospital of CPLA, Beijing, 100048, PRC 【Abstract】 The new edition of WHO classification of tumors of soft tissue and bone had been formally published in 2013, which reflected the consensus of 159 experts from 24 countries and districts. The authors compared the changes in this book with the old edition ( 2002 ) and summarized its influence to clinical managements from the view of an orthopedic oncologist. In general, the concept of intermediate tumor was re-proposed in classification of tumors of bone, and was subdivided into two groups, locally aggressive and rarely metastasizing. Some tumors were subjected from benign tumors to intermediate tumors and the behavior was coded / 1 for borderline or uncertain behavior. The most important modification was that grade I chondrosarcoma was not considered as malignant tumor and can be treated as intermediate tumor. Malignant fibrohistocytoma was renamed as undifferentiated high-grade pleomorphic sarcoma which is the most important glossological change. As to the soft tissue aspect, the classification was more complicated than that of bone and changes were made in various tumors, but its influence to clinical management was limited. The surgeons’ better understanding of up to date classification of bone and soft tissue tumors