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姓 名 Zhixin 性 别 M 出生年 Feb. 1973 tian 月 出生地 Hunan 婚姻状况 Marri 政治面 ed 貌 国 籍 China 从事专业 Biological Separations and MS 现工作单位及职位 Pacific Northwest Natl. Lab, Post doctorate 人事关系所在单位 中国科学院人才交流中心 学习及工作经历： （从大学开始填，内容包括时间、单位、学位、所学专业、从事专业、专业技术 职务情况，时间段要连续，准确到月份） Aug. 2008 – present, Pacific Northwest National Laboratory, USA, Biological Separations and Mass Spectrometry, Post doctorate Research Associate Mar. 2004 – Jul. 2008, University of Minnesota, USA, Physical Organic Chemistry, Post doctorate Sep. 2000 – Feb. 2004, Beijing Institute of Chemistry, CAS, Physical and Analytical Chemistry, Ph.D. Sep. 1997 – Jul. 2000, Hunan Normal University, Organic Synthesis, M.S. Sep. 1993 – Jul. 1997, Hunan Normal University, Chemistry, Undergraduate 如内容较多，本栏目填不下时，可另纸接续（下同）。 2 主要学术成就、科技成果及创新点： 1) First High-throughput and high-sensitivity study of histone post-translational modifications using self-built two-dimensional reversed phase liquid chromatography-weak cation exchange-hydrophilic interaction liquid chromatography (RPLC-WCX-HILIC) coupled to Theromo LTQ Orbitrap Velos. Up to 1000 histone isoforms have been identified using several micro grams of HeLa core histones, which represents a progress of 10 times more identifications with 100 times less sample comparing to all of the other related studies. This progress will greatly advance epigenetics related to histone modifications. This work has been submitte to Nature Method. 2) First finding of the dependence of gas-phase structures of electrospray ions on the solvent as highlighted in Chem. Eng. News [2008, 86(32), 38]: Does Electrospray Ionization Produce Gas-Phase or Liquid-Phase Structures? (see Paper 31 and 36 for the detail) 3) Discovery of the most b