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单四级杆和三重四极杆gc-Experimental
Comparison of Single and Triple Technical Note 10431
Quadrupole GC-MS Instruments for
Full Scan Analysis of Semivolatile
Organic Compounds
Amit Gujar,1 Paul Silcock,2 and Alexander Semyonov1
1Thermo Fisher Scientific, Austin, TX, USA;2 Thermo Fisher Scientific, Runcorn, UK
Key Words
Full Scan Acquisition, LOD, Semivolatile Organic Compounds,
Spectral Quality
Introduction
Single quadrupole mass spectrometers, such as the
Thermo Scientific? ISQ? Series GC-MS system, are
a popular choice among analysts using GC-MS for
compound identification and quantitation in relatively
simple matrices. However, triple quadrupole mass
spectrometers such as the Thermo Scientific? TSQ? Duo
GC-MS/MS and TSQ? 8000 Evo GC-MS/MS systems
have been gaining popularity due to their high selectivity
and lower detection limits, especially in complex matrices.
The higher cost of triple quadrupole instruments is one
of the main barriers to their adoption by analytical labs,
however, the cost differential between single and triple
quadrupole mass spectrometers has decreased in recent Experimental
years such that today, triple quadrupole instruments are a
Sample and sample preparation: Use Restek 8270
viable alternative to their single quadrupole counterparts.1
MegaMix? as the source of semivolatile organic
An o
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