跨膜运输与信号传递新5.pptVIP

酪氨酸激酶 ①胞质酪氨酸激酶：如Src、Tec、ZAP70、JAK； ②核内酪氨酸激酶 ：如：Abl、Wee； ③受体酪氨酸激酶（RTKs） ： Signaling ligands of RTKs: 1.Nerve growth factor (NGF) 2.Platelet-derived growth factor (PDGF) 3.Fibroblast growth factor (FGF) 4.Epidermal growth factor (EGF) 5.insulin and insulin-like GF(IGF-1) 6.vascular endothelial factor(VEGF);Figure?15-47?Six subfamilies of receptor tyrosine kinases.????Only one or two members of each subfamily are indicated. Note that the tyrosine kinase domain