PULMONARY HYPERTENSION-肺动脉高压.ppt

PULMONARY HYPERTENSION; INTRODUCTION BRIEF HISTORY WHAT IS PH? WHAT CAUSES PH? SIGNS AND SYMPTOMS DIAGNOSIS OF PH TREATMENT OF PH ;INTRODUCTION;Millions of people are affected by a condition known as high blood pressure (hypertension) whereby the blood travels through the body’s arteries at a pressure higher than normal. PULMONARY HYPERTENSION is a far less common type of high blood pressure that affects specifically the arteries in the lungs. Pressures in the lung arteries are normally significantly lower than the pressures in the systemic circulation. Pulmonary hypertension occurs when the pressure in the pulmonary circulation becomes abnormally elevated. It is a serious condition that becomes progressively worse and eventually proves fatal. ;INTRODUCTION;H I S T O R Y;WHAT IS PULMONARY HYPERTENSION?;Ordinarily, blood vessels in the lungs provide less resistance to blood flow than blood vessels in the rest of the body do. Hence, blood pressure is usually much lower in the lungs. While pressure in general circulation is about 120/80 mm Hg, in the pulmonary arteries, it is only around 25/15 mm Hg. Mean (average) pulmonary artery pressure = number between highest and lowest pressures Normal at rest : 14 mm Hg Pulmonary hypertension at rest : 25 mm Hg during exercise : 30 mm Hg;Primary Pulmonary Hypertension no underlying cause for the high blood pressure in lungs likely to begin with spasm of the muscle layer in pulmonary arteries patients are rather sensitive to substances that cause blood vessels to constrict may have an inherited predisposition for the disease Secondary Pulmonary Hypertension results directly