18FFDG PET - CT detection of the clinical value of bone metastases.doc

 PAGE \* MERGEFORMAT 18 18FFDG PET / CT detection of the clinical value of bone metastases Of: Wang Yonghong, Chen New Linmei Fu, Zhou Shuo, HE Pin-Yu, Chen David [Abstract] Objective To evaluate the 2 [18F] fluoro 2 deoxy glucose (18F FDG) PET / CT imaging in the diagnosis of bone metastases. Methods Retrospective analysis of 118 cases confirmed to be malignant in patients with bone metastases 18F FDG PET / CT scan, the researchers morphological characteristics of bone metastases and metabolic characteristics of the relationship and metabolic characteristics of bone metastases and the relationship between the primary tumor, and compared some patients 18F FDG PET / CT imaging with 99mTc methylene diphosphonate salt (99mTc MDP) bone scan results. osteolytic and mixed results to show the high metabolic changes in the main lesion, they were changed and osteogenic lesion and no change in lesion density comparison, the difference was significant (P lt;0.05) .18 F FDG PET / CT imaging and 99mTc MDP bone scan detection of bone metastasis were 90.4% sensitivity, 94.2%, specificity was 98.8%, 46.9%, accuracy was 92.9%, 86.7% .18 F FDG PET / CT imaging in diagnosis of bone metastases the sensitivity of 99mTc MDP bone scan with no significant difference, but a higher specificity and accuracy. Conclusions 18F FDG PET / CT imaging of bone metastases and may reflect and metabolic characteristics of different forms than 99mTc MDP bone scan has a higher specificity and accuracy for early diagnosis of multiple bone metastasis of cancer. [Keywords:] bone tumor; organic technetium compounds; deoxyglucose; fluorine radioisotopes; Tomography, emission computed Malignant tumor metastasis is one of the most serious hazard is the main reason cancer patients clinically dead. Many advanced cancer bone metastasis can occur to lung cancer, breast cancer, stomach cancer, prostate cancer, and so is more common. Early diagnosis of cancer on the accuracy of bone metastases were t