4603 cases of blood culture pathogen species distribution and antibiotic resistance.docVIP

 PAGE \* MERGEFORMAT 14 4603 cases of blood culture pathogen species distribution and antibiotic resistance [Abstract] Objective monitoring and analysis of hospital infection in the last two years of pathogens in blood culture characteristics of distribution and drug resistance, in order to provide the latest clinical basis for anti-infective therapy. Methods VITEK system, identification of bacteria, Kirby  Bauer agar diffusion method for in vitro drug sensitivity test, the application software analysis WHONET5.3 samples isolated from blood culture pathogen distribution and drug susceptibility results. Results 4603 cases were detected in 587 blood culture pathogens, including Gram-negative bacteria 383 (accounting for 65.25%), Gram-positive bacteria 180 (accounting for 30.66%), fungal 24 (accounting for 4.09%). Imipenem and meropenem against Escherichia coli and Klebsiella pneumoniae The effect is better, but right-resistant Acinetobacter baumannii more serious, drug-resistant rate of 35% or more. Producing ESBLs in Escherichia coli and Klebsiella pneumoniae the detection rate of 61.24% and 48.91%. Glycopeptides and linezolid antimicrobial agents against Gram-positive cocci is highly sensitive. Staphylococcus MRSA and MRCNS detection rates were 75.47% and 66.67%. Conclusions At present, our hospital pathogens isolated from blood culture species are widespread and drug resistance are quite different pairs of blood culture isolates from early detection and drug resistance analysis is very necessary and reasonable for clinicians to provide an important basis for application of antimicrobial agents to prevent the abuse of antibiotics and the new drug resistant strains. [Keywords:] blood culture; pathogenic bacteria; antibacterial drugs; bacterial resistance; hospital infection ABSTRACT Objective A surveillance and analysis were performed to investigate the characteristics of distribution and antimicrobial resistance of microorganisms isolated from blood cultur