About JGC capsules determination Geniposide.docVIP

 PAGE \* MERGEFORMAT 9 About JGC capsules determination Geniposide [Abstract] Objective To establish Abrus Capsules HPLC Determination of geniposide. Methods Lichrospher C18 column (5 μm, 4.6 mm × 250 mm), acetonitrile -0.1% phosphoric acid (10:90) as mobile phase flow rate: 1.0 mL / min, detection wavelength: 238 nm, column temperature: 35 ℃. geniposide results in the range of 0.14 ~ 1.68 μg linear regression equation was: Y = 1 552.15X-6.42, r = 0.999 9, recovery was 97.53% (RSD = 1.24%, n = 6). Conclusion The method is stable, reliable, and can be used for the preparation of quality control. Keywords:] high performance liquid chromatography, JGC capsule, geniposide Determination of Geniposide in Jigucao Capsule By HPLC WANG Yan-hong, CHEN Xian Guangxi Yulin Pharmaceutical Co.Ltd., Yulin 537001, China Abstract: Objective To estabilish a HPLC method for the determination of Geniposide in Jigucao Capsule. Methods The column was Lichrospher-C18 (5 μm, 4.6 mm × 250 mm). The determination was carried out with acetonitrile-0.1% phosphoric acid (10: 90) as the mobile phase, a flow rate of 1.0 mL / min and detected at 238 nm, and temperature of the column was 35 ℃. Results The calibration curve showed good linearity in the range of 0.14 ~ 1.68 μg, Y = 1 552.15 X-6.42, r = 0.999 9. The mean recovery was 97.53% (RSD = 1.24%, n = 6). Conclusion The method is accurate, reliable, and can be used for quality control of the preparation. Keywords:: HPLC, Jigucao Capsule; Geniposide Abrus capsule Shuganlidan, detoxification of power, for acute and chronic hepatitis and cholecystitis, liver and gallbladder damp-heat syndrome who are, by JGC, gardenia, capillaries, etc. Smell the Prescription. Abrus a square in the herbs, but because of the herb plants are relatively weak chemical research work, not yet meet the requirements of reference standard determination can not control its content. capillaries as Fangzhong Chen drugs, chlorogenic acid, the main effec