About Strychnos and its different processed products of water to cook the things Strychnine and brucine determination of.docVIP

 PAGE \* MERGEFORMAT 10 About Strychnos and its different processed products of water to cook the things Strychnine and brucine determination of [Abstract]: Objective HPLC method Strychnos processed products of Jiangxi law and improved method of decoction extracts processed products Strychnine and brucine were determined alkali content. Methods fillers for the silica gel column, mobile phase hexane - dichloromethane - methanol - concentrated ammonia (47.5:47.5:5:0.35), the detection wavelength was 254 nm. the results of processed products of Jiangxi method processed products and improved method of strychnine and brucine in at low levels. which fried in vinegar in the sand content of the lowest. Conclusions of Jiangxi and its improved method of Strychnos cooked hot sand method than the method easier to reduce toxicity and fried to make it safe range increases, so clinical use to improve their security. [Keywords:] Strychnos processing disabilities Ningma brucine determination by high performance liquid chromatography Abstract: Objective HPLC method was used to determine strychnine and brucine in the decoction of Semen Strychni and its processed products of Jiangxi methods and innovated methods. Methods SiO2 was used as the stationary phase, n-hexane: dichloromethane: methanol: ammonia (47.5: 47.5:5:0.35) as the mobile phase, with detection wavelength at 254 nm. Result The contents of strychnine and brucine in the processed products of Jiangxi methods and innovated methods were low. The content of that in acetic acid-soaked product scalded with hot sand was the lowest. Conclusion Semen Strychni and its processed products of Jiangxi methods and innovated methods can lower the toxicity and improve the safety of clinical use. Keywords:: Strychnos nux-vomica L., processing; strychnine, brucine, HPLC, determination Strychnos nux plants for the Strychnos nux-vomica L. dry mature seeds. Main component alkaloids, mainly strychnine, followed by strychnine,