About two regimens of mifepristone for termination of pregnancy big Evaluation of the month.docVIP

 PAGE \* MERGEFORMAT 8 About two regimens of mifepristone for termination of pregnancy big Evaluation of the month [Keywords:] large dosage regimen of mifepristone to terminate pregnancy Evaluation of the month With the development of medical abortion techniques, the use of mifepristone with misoprostol (referred to as misoprostol) for big month (11 to 18 weeks) of pregnancy abortion, has been increasingly widely used clinically, but there is still no complete standardized treatment program, to explore the great month of pregnancy, this medication abortion drug mifepristone best way big month in our hospital 192 cases of voluntary pregnancy requires abortion, use of oral low-dose regimens of mifepristone with termination of pregnancy in the big month, and achieved satisfactory results, are reported below. Subjects and methods 1. PARTICIPANTS: March 2004 ~ May 2008 11 to 18 weeks after stopping the requirements of our hospital 384 cases of abortion healthy women, menstrual regularity, gynecological examination and B-ultrasound diagnosis of intrauterine fetal life, blood, urine and liver and kidney function was normal and no contraindications to medical abortion. the abortion drug program by 384 cases were divided into 2 groups, mifepristone 50 mg group (50 mg group) 192 patients, mifepristone 75 mg group ( 75 mg group) 192 patients, group 2 compared clinical characteristics of abortion, no statistically significant difference (Pgt; 0.05), comparable, see Table 1. Table 1 Comparison of clinical features (+-s) 2. Medication Methods: 50 mg group, 50 mg mifepristone orally, every 12 h 1 times, a total of 3 d, the early morning on day 4 of oral misoprostol 600 μg, 400 μg misoprostol powdered into the posterior fornix; 75 mg group, mifepristone 75 mg, every 12 h 1 times, a total of 2 d, 3 days morning start using misoprostol, the method with the observation group, 2 groups of fasting before and after service misoprostol 2 h, and observed to be aborted c