After thrombolytic therapy for acute myocardial infarction plasma brain natriuretic peptide levels and the recent clinical prognosis.docVIP
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After thrombolytic therapy for acute myocardial infarction plasma brain natriuretic peptide levels and the recent clinical prognosis
[Abstract] Objective To investigate the thrombolytic therapy of acute myocardial infarction (AMI) of plasma brain natriuretic peptide (BNP) level and clinical prognosis in the near future. Methods Patients with AMI in 2007-2009, 73 patients received intravenous thrombolysis with reteplase treatment, according to whether vessel recanalization after thrombolysis, into a successful group and unsuccessful thrombolysis group and 26 patients not receiving thrombolysis patients as control group. thrombolysis before 7d after thrombolysis, plasma BNP, record 1 month of major cardiovascular events. The results between the 3 groups before thrombolysis BNP levels were not significantly different, the plasma BNP 7d after thrombolysis were 202.2 + -54.1pg/ml, 532.3 + -65.8pg/ml, 572.3 + - 68.3pg/ml, BNP was significantly lower than the success group and control group was not successful, with a significant difference, P lt;0.05.1 month incidence of major cardiovascular events was 9%, 27%, 27%, success was significantly lower than through group and control group, P lt;0.05. Conclusions Reteplase reperfusion therapy can significantly reduce plasma BNP levels in patients with myocardial infarction to reduce cardiovascular events in the near future.
[Keywords:] brain natriuretic peptide in cardiovascular events of myocardial infarction thrombolytic therapy Is the primary hospital thrombolytic treatment of acute myocardial infarction an important measure, AMI early successful reperfusion to prevent left ventricular remodeling and reduce cardiovascular events, an effective way to protect the heart function. BNP is an increase in blood volume and pressure overload stimulation mainly by the ventricle of a peptide hormone secreted, AMI increased after the BNP, suggesting that infarct area, poor cardiac function. lowe
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