Continuous blood purification therapy on multiple organ dysfunction prognosis.docVIP

 PAGE \* MERGEFORMAT 10 Continuous blood purification therapy on multiple organ dysfunction prognosis [Abstract] Objective: The multiple organ dysfunction in ICU (Multiple organ dysfunction syndrome, MODS patients with continuous blood purification therapy (continuous blood purification CBP), of its various cytokines and inflammatory mediators (such as tumor necrosis factor / TNFa, IL 1,6 / IL 1,6, etc.) remove the effect of CBP for the treatment of MODS. Methods: 200612-200808 month of treatment in our hospital 38 cases of ICU patients randomized MODS , A conventional drug therapy group, B group in addition to conventional medical treatment of drug treatment, application of CBP was observed before and after treatment of cytokines and inflammatory mediators changes, and survival rates of the two groups were compared. Results: CBP treatment and integrated treatment for routine medical clearance MODS for the various effects of cytokines and inflammatory mediators were significantly different compared (P lt;0.01, can reduce mortality in patients with MODS (P lt;0.01. Conclusion: CBP MODS when the body can remove inflammatory cytokines to maintain homeostasis, reducing MODS mortality rate. [Keywords:] blood, purification, multiple organ dysfunction, inflammatory mediators, cytokines [ABSTRACT] Objective: To study the prognosis of multiple organ dysfunction syndrome treated by continuous blood purification.Evaluate its effect in clearing the various inflammatory medinums and cytokines, such as TNFa, IL 1, IL 6 et al.Methods: In this case, 38 patients who diagnosed MODS were divided into two groups, patients in Group A received routine therapy, and patients in Group B accepted CBP besides the routine therapy.Results: In MODS, CBP can clear the various inflammatory mediums and cytokines more efficiently than that of the routine therapy.Also, the mortality of group B was significantly lower than that of group A. The difference between the two groups was signif