Diabetic nephropathy in Chinese medicine research.docVIP

 PAGE \* MERGEFORMAT 33 Diabetic nephropathy in Chinese medicine research Keywords: Diabetic nephropathy Diabetic Nephropathy (Diabetic Nephropathy, DN) is a serious microvascular complication of diabetes. Is a serious threat to human health, common and frequently-occurring disease, is also the home of great concern to clinical research. According to reports, history of diabetes for 10 years to 20 years the incidence of patients with DN up to 47.66% [1], and the lesions showed progressive development, can be 5 to 10 years after the emergence of end-stage renal failure. Therefore, how to effectively prevent the development of diabetic nephropathy, lower or reduce the disability of diabetic nephropathy and the fatality rate is an important topic in clinical medicine. In recent years, Chinese medicine will now progress in prevention and treatment of diabetic nephropathy are summarized below: 1 Experimental Study of Chinese Medicine to Combat DN 1.1 Single Herbs of the active ingredient and its preparation Yang Jun-Wei, Lei-Shi et al [2] on the treatment of experimental diabetic nephropathy rhubarb mechanism of action conducted in-depth study. The results show that rhubarb can improve renal function in experimental animals and suppress kidney hypertrophy, reduce proteinuria, improve lipid metabolism disorder of diabetic nephropathy, lowering blood glucose and glycated hemoglobin levels. And can reduce the kidney of diabetic nephropathy the phenomenon of high oxygen. Tip of rhubarb on experimental DN have positive effects. Zhang Ying et al [3] research Scutellarin yuan (EB) on the protective effect of kidney of diabetic rats and concluded as: EB may be localized by reducing the renal endothelin (ET) and transforming growth factor β1 (TGF  β1 ) content to play on the protective effect of DN. Wang Rao et al [4] To observe the fungus on protective effect of kidney of diabetic rats. The results showed that Ganoderma lucidum