[科学].Science.07.October.2011---藻华治理与营养盐_气温关系.pdfVIP

PERSPECTIVES tion from microbiota-disease associations is eases correlated with modi? cations of the gut intestinal diseases and metabolic diseases dif? cult. Moreover, bacteria to which health microbiota, such as irritable bowel syndrome such as obesity and diabetes. We are still bene? ts have been attributed, such as Faeca- and in? ammatory bowel diseases. These indi- only at the beginning stages of considering libacterium prausnitzii ( 14), have not been viduals often adhere to self-imposed diets microbiomes as a diagnostic and engineering associated with a particular enterotype. Thus, that they have empirically found to reduce microbiome structure as treatment. although the enterotypes represent a useful symptoms such as diarrhea, but are unlikely References framework for the study of the gut micro- to anticipate that an arti? cial sweetener may 1. U. Gophna, K. Sommerfeld, S. Gophna, W. F. Doolittle, biota, the clinical value of knowing one’s affect their indigenous microbiota and possi- S. J. Veldhuyzen van Zanten, J. Clin. Microbiol. 44, 4136 enterotype remains to be determined. bly their well-being. (2006). 2. C. Manichanh et al., Gut 55, 205 (2006). Wu et al. also show that several dietary It is anticipated that the study by Wu et al. 3. D. N. Frank et al., Proc. Natl. Acad. Sci. U.S.A. 104, factors that have an impact on gut bacteria, will be followed up by larger diet-microbi- 13780 (2007). such as red wine and the arti? cial sweetener ome association studies that will help re? ne 4. P. D. Scanlan et al., Environ. Microbiol. 10, 789 (2008). 5. T. Wang et al., ISME J. 10.1038/ismej.2011.109 (2011). aspartame, are not correlated with enter