Etiology and pathogenesis of erythroderma Research Progress.docVIP

 PAGE \* MERGEFORMAT 12 Etiology and pathogenesis of erythroderma Research Progress [Keywords:] erythroderma; etiology; mechanism; Progress Erythroderma, also known as exfoliative dermatitis, is a serious skin disease, first described in 1886 by the Hebra. Clinical manifestations of diffuse flushing of skin, swelling, infiltration, desquamation, total body skin area of #8203;#8203;90%, while can lead to visceral injury and metabolic disorders, caused by a variety of reasons for the syndrome, clinical mortality rate in the foreign reports about 10% to 20%, about 10% of the country [1]. erythrodermic cause complex can be secondary to other skin diseases, drug reactions, malignancies and idiopathic erythroderma. cytokines and their receptors, adhesion molecules, and their chromosome function mutations in the pathogenesis of staff may. In recent years, and the cause of the disease In further studies of pathogenesis, this article reviewed. A disease due to 1.1 secondary to other skin diseases According to the literature, often erythroderma secondary to psoriasis, eczema, contact dermatitis, atopic dermatitis, pityriasis red hair, chronic actinic dermatitis, seborrheic dermatitis, pemphigus, dermatomyositis, systemic lupus erythematosus, lichen planus, etc. [2 5]. Foreign Benmously [3] reported 80 cases of erythroderma secondary to the original skin disease in 58 cases, including cases of psoriasis 4l, accounting for 51.25%, eczema 6 cases, accounting for 7.5%, 5 cases of pemphigus, accounting for 6.25%, generalized fungal skin disease in 3 cases, accounting for 3.75%, scabies, hair red rosea, lichen planus and 1 cases, accounting for 1.25%; drug reactions in 9 cases, accounted for 11.25%; skin T cell lymphoma (CTCL) 7 cases, accounting for 8.75%; 6 cases of unknown cause, accounting for 7.5%. Domestic Fan Ming et al [4] reported 52 cases of erythroderma in the skin secondary to the original 26 cases, including 21 cases of psoriasis, accounting for 40.