Excessive application of Metoclopramide-induced extrapyramidal symptoms in 2 cases in children.docVIP

 PAGE \* MERGEFORMAT 6 Excessive application of Metoclopramide-induced extrapyramidal symptoms in 2 cases in children [Keywords:] Metoclopramide extrapyramidal symptoms in children 1 Case Information Case 1: children with female, 8 months, due to acute diarrheal disease outbreaks and vomiting, local clinics to give metoclopramide (metoclopramide, manufacturer and lot number unknown) 10 mg intramuscular injection, about 1 h after the children appeared eyes on the turn, head thrown back, showed anti-Zhang-shaped bow angle, and lasted about 3 min, after mitigation, to consider as having viral encephalitis emergency come to my hospital for treatment. Admission examination: development of normal, clear consciousness, crying, irritability, anterior fontanelle flat, heart, lungs, abdomen no abnormalities, and normal limb muscle strength and muscle tone, meningeal irritation sign (-). Related auxiliary examination: blood, urine, feces routine and biochemical series, EEG were normal. Diagnosis of Metoclopramide-induced extrapyramidal reaction to excess. Atropine 0.01 mg / kg subcutaneously, while giving the energy mixture intravenous drip. Children admitted to hospital after the illness does not recur again, the hospital for observation and discharged 2 d. Case 2: children male, 5 years old, accompanied by vomiting due to acute bronchial pneumonia, the local clinic to give metoclopramide (manufacturer and lot number unknown) 15 mg intramuscular injection of about 3 h after limb tremor, and neck muscles paroxysmal right to reverse the spasm. 2 h after the onset diagnosis and treatment of my subjects. Admission examination: consciousness-ching, crying, questioning can be a correct answer to neck strong (± ), bilateral pulmonary rales may be heard and wet, heart and abdomen revealed no abnormalities, and normal limb muscle strength, muscle tension slightly higher g s sign (-), Brandt sign (-), other nervous system revealed no positive signs. Related auxiliary examinati