Ganciclovir treatment of children with combined Shuanghuanglian HFMD Observation of 41 Cases.docVIP

 PAGE \* MERGEFORMAT 9 Ganciclovir treatment of children with combined Shuanghuanglian HFMD Observation of 41 Cases [Abstract] Objective To investigate the combined ganciclovir treatment of children with hand, foot and mouth disease Shuanghuanglian the clinical effect. Methods 82 cases of hand, foot and mouth disease children were randomly divided into treatment group and control group 41 cases, 41 cases Both groups were fever, fluid replacement and other symptomatic treatment, intravenous ganciclovir treatment group injection 5 mg / (kg · d) and oral shuanghuanglian 5 ~ 10 ml / time, 3 times a day in the control group were given ribavirin injection 10 ~ 15 ml / (kg · d) treatment, clinical symptoms and signs of change and improve the time for analysis. Results The clinical symptoms and signs disappeared earlier than those in the control group (P lt;0.01), improved less than the control group, treatment group, 90.73% total efficiency, the efficiency of the control group was 70.73%, the difference was significant (P lt;0.01). Conclusion Ganciclovir treatment of children with combined Shuanghuanglian HFMD short course, quick, no adverse reactions should be widely applied. [Keywords:] hand foot and mouth disease in children ganciclovir Shuanghuanglian Period of HFMD in children (especially under age 5) of the more common skin and mucosal acute infectious diseases, there is a growing and serious in recent years the trend is no longer a minor infection. Lesions mainly in the hand, foot and palm, hip and oral herpes and other parts. clinical manifestations were fever and oral ulcers, hand, foot and herpes, easy to secondary bacterial infection. treatment as soon as possible to reduce symptoms and shorten the course for the key. previous ribavirin treatment for general use, while strengthening support for symptomatic treatment, but ineffective. We January 2008 to January 2009 in Wuhan, Wuchang hospital diagnosed 82 cases of hand, foot and mouth disease childr