Gansu and Qinghai trichocarpa Aconitum alkaloids extracted and identified.docVIP

 PAGE \* MERGEFORMAT 13 Gansu and Qinghai trichocarpa Aconitum alkaloids extracted and identified [Abstract] Objective: Identification trichocarpa Purification Gansu and Qinghai Aconitum Alkaloids. Methods: natural herbs after drying at room temperature, splintered, with the alkaline precipitation method of acid extracted alkaloid extracted, and then silica gel column chromatography monomer alkaloids were isolated by using chemical method and spectral method for testing the structure. RESULTS: 10 compounds identified by the structure, of which six C19 diterpene lactone alkaloids, four C20 diterpenoid alkaloids . Conclusion: The obtained 10 pure monomer alkaloids. [Keywords:] trichocarpa Gansu and Qinghai Aconitum; separation; lipid-type diterpenoid alkaloids C19 Aconitum (Aconitum) of plants belonging to Ranunculaceae (Ranunculaceae), mostly in the north temperate zone, the whole world about 350 species, of about 170 species [1], this genus is the most resource-rich countries [2], mainly in southwestern provinces. this genus, recorded in Chinese Pharmacopoeia as official medicinal, there are two, Aconitum (monkshood) and Aconitum, but the actual person as about 40 species of medicinal [3], has analgesic, sedative, rheumatism treatment of bruises, cough, fever and other effects. Diterpene alkaloids of the species and characteristics of the main chemical components. Because of its complicated structure, physiological activity significantly, which caused a great interest in plant chemical workers. Since the 70s of last century, along with analytical techniques, especially the identification of NMR in structural analysis of the extensive application of chemistry of diterpenoid alkaloids have also been a rapid development. So far, 160 species of Aconitum has conducted a chemical study of plants, the resulting multi-component for the C19 diterpene alkaloids. diterpenoid alkaloids of this genus is not only active ingredients and toxic components, and is al