Gastrointestinal stromal tumors of the clinical features and prognosis of.docVIP

 PAGE \* MERGEFORMAT 15 Gastrointestinal stromal tumors of the clinical features and prognosis of Author: Cai Wei-Long Han Chun Fan, Ng Hok-fen Keywords: gastrointestinal stromal tumor Gastrointestinal stromal tumor (gastrointestinal stromal tumors, GIST) are relatively rare, is a class of gastrointestinal non-epithelial-derived stromal tumor, malignant tumors of the gastrointestinal tract accounts for 1% ~ 3%, biological behavior from potentially malignant to the malignant process. GIST hide symptoms, preoperative diagnosis difficult, complex and biological characteristics, there is no a very clear criteria for judging the prognosis. This retrospective analysis of our hospital from January 2001 to July 2007 admitted cases of gastrointestinal stromal tumors clinical and follow-up data to explore the GIST analysis of the clinical features and prognostic factors. 1 Data and methods 1.1 General Information From January 2001 to July 2007 a total of 95 patients were diagnosed as gastrointestinal stromal tumors, including 2 cases with gastric cancer, 2 cases with colorectal cancer, not included in this group analysis. This set of practical cases of 91 cases, 53 cases were male and female 38 cases, with an average age of 52 years. 1.2 Treatment 91 patients underwent surgical treatment, of which 84 cases of complete resection, 7 cases of palliative surgery. 8 cases with distant metastasis, metastasis rate was 8.8% (8 / 91), of which 5 cases of liver metastasis, peritoneal metastasis in 3 cases. 1.3 Statistical Methods Using SPSS 12.0 software for processing. Single-factor analysis application log-rank test, multi-factor analysis applied Cox regression analysis, application χ2 test parameters compared between the two groups statistically significant. 2 Results 2.1 Clinical features This group of patients with surgically clear tumor site, where 50 cases of stomach, small intestine, 32