Hemoglobin concentration and the effect of radiotherapy for nasopharyngeal carcinoma.docVIP

 PAGE \* MERGEFORMAT 13 Hemoglobin concentration and the effect of radiotherapy for nasopharyngeal carcinoma [Abstract] Objective: To investigate the nasopharyngeal carcinoma (NPC) patients with hemoglobin concentration (HBC) on the efficacy of radiation therapy. METHODS: A retrospective analysis of 1 January 2001 ~ December 31, 2004 the NPC received radical radiotherapy The clinical data of 336 patients, divided according to HBC anemia before radiotherapy group (men lt;120 g / L, female lt;110 g / L) and normal group (Mgt; = 120 g / L, womengt; = 110 g / L), According to radiation before and after the change of HBC into HBC decreased group (radiotherapy at the end of HBC lt;before radiotherapy) and HBC did not drop group (radiotherapy at the end of HBCgt; = before radiotherapy). using electron linear accelerator 8MV X line conventional fractionated external beam compare the local control rate among the groups and the 5-year survival. Results: anemia group and normal local control rate between groups was not significant (Pgt; 0.05, anemia group and normal group, 5-year survival rates were 35.12% and 55.36%, the difference was statistically significant (P lt;0.01). the normal group, HBC decreased after radiotherapy group did not decline in 5-year survival rate was lower than that, but the difference was not statistically significant (Pgt; 0.05, anemia group HBC decreased after radiotherapy group, 5-year survival rate was significantly lower than those without decreased, the difference was statistically significant (P lt;0.01). Conclusion: HBC before radiotherapy in patients with nasopharyngeal carcinoma may affect local control rate of radiotherapy and 5-year survival rate . [Keywords:] nasopharyngeal carcinoma, radiotherapy, hemoglobin, prognosis Correlation between hemoglobin concentration and the radiotherapy efficiency in patients with nasopharyngeal carcinoma [ABSTRACT] Objective: To investigate the correlation between hemoglobin concentration (