Kalman filter UV Spectrophotometry compound paracetamol tablets () in the 3-component.docVIP

 PAGE \* MERGEFORMAT 9 Kalman filter UV Spectrophotometry compound paracetamol tablets () in the 3-component Of: Cai Zhuo Zhao Jing Jiang Caiying book Molly Molly Jun Liang Xinyuan [Abstract] purposes Kalman filter (KF combination with UV spectrophotometry, the establishment of a simultaneous determination of acetaminophen ?p isopropyl antipyrine and caffeine in new ways. Methods 220 ~ 290 nm in the UV wavelength range 2 nm measured every 16 sets of standards should be mixed solution to the absorption coefficient matrix, the test solution absorbance input Kalman filter procedure for content analysis. In this study, the filtering process monitoring are discussed, paracetamol ?p Isopropyl Antipyrine and caffeine filter frequency of 36 times. results to predict the 3 components of the sample, the average recoveries were 98.6% and 106%, 103%, the actual samples, the average recoveries were 103%, 101 %, 96.2%. Conclusion The method does not need separation of samples, simple operation with satisfactory results. [Keywords:] Spectrophotometry, Kalman filter (KF, acetaminophen, isopropyl antipyrine, caffeine Compound paracetamol tablets ( called hash-pass, the main ingredients are acetaminophen (APAP), isopropyl antipyrine (PP), caffeine (CAF), is antipyretic analgesic compound . acetaminophen anti-inflammatory drugs are aniline, has been widely used, isopropyl antipyrine are pyrazolone anti-inflammatory drugs for the treatment of headache, toothache, neuralgia and fever, etc. Clinical use of safety and found no adverse reactions have been set by the multinational Pharmacopoeia, caffeine can enhance the analgesic effect. now that the report found only in 3-component high performance liquid chromatography to study the pharmacokinetics of [1]. UV Spectrophotometry is a simple, rapid, simple methods of analysis, but in the absorption spectra overlap between the components of the situation, can not be directly used for quantitative analysis by UV spectrophotome