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Lin busulfan Extraction of cancer pills
PAGE \* MERGEFORMAT 8
Lin busulfan Extraction of cancer pills
[Abstract] Objective White Lotus orthogonal design eliminate cancer pill extraction. Method of total extraction rate, extraction rate scutellarin index, select the amount of water (times the number of extraction, extraction time (h order to investigate factors orthogonal experiments L9 (34 identified cancer lotus white pill extraction consumption. Results The optimum conditions for extracting 3 times, respectively, the amount of water 8 times, 6 times, 4 times the amount of extraction time were 2,1.5, 1 h. Conclusion amount of water, extraction times and extraction time have significant effects on the process.
[Keywords:] Lin busulfan cancer pills, extracts, scutellarin, orthogonal
Lin Department of busulfan clinical experience in cancer pill side for liver cancer, gastric cancer treatment. Prescribed by the barbata, Hedyotis diffusa, Pinellia, astragalus and other herbs composed of 15, with heat detoxification, swelling Sanyu and other effects. is to choose water as a solvent and the yield of total water extract, the extraction rate scutellarin index [1 ~ 3], extraction of them. According to pre-test results, the use of L9 (34 orthogonal Experimental Optimization of extraction conditions for the elimination of white lotus Process cancer pill reference.
1 apparatus and materials
1.1 Instrument Shimadzu HPLC system, including the LC-10ATVP pump, SPD-10AVP UV detector, science oven, Ckchrom-ehromatography data acquisition system, BP211D type analytical balance (Sartorius, Germany.
1.2 The prescription of Chinese herbal materials were purchased from medicine company, Zhengzhou City, Henan Medical College by Professor Chen Suiqing identification are authentic. Scutellarin reference substance (China Pharmaceutical and Biological Products provides for the determination of use, Lot :880 -200,701 , content of 96.14%, HPLC pure methanol, and other reagents were of analytical grade. banzhili
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