MMP-9 protein and microvessel density in endometriosis and its significance in the expression.doc

 PAGE \* MERGEFORMAT 13 MMP-9 protein and microvessel density in endometriosis and its significance in the expression [Abstract] Objective To study the MMP-9 and microvessel density (MVD) value in endometriosis (endometriosis) in patients with ectopic endometrial tissue, to explore its relationship with the development of EMs. Methods immune was used to detect 45 cases of ectopic endometrial tissue and 15 cases of control in endometrial tissue MMP-9 expression and microvessel density. Results (1) ectopic endometrial cells in the expression of MMP-9 was significantly higher than in bit endometrium and control endometrium; (2) microvessel density in ectopic endometrium was significantly higher than that of eutopic and control endometrium; (3) MMP-9 and microvessel density in ectopic endometrium there is no correlation between the expression (Pgt; 0.05), endometrial expression in control and no correlation (Pgt; 0.05). Conclusions MMP-9, microvascular density in endometriosis increased expression of the ectopic endometrium, which The results may be related to invasion of ectopic endometrium. [Keywords:] Endometriosis; MMP-9; microvessel density; immunohistochemistry Abstract Objective To study the expression of MMP-9 and microvessel density (MVD) in ectopic endometrial tissue of the patients with endometriosis (EMs) and to explore its relationship with the occurrence and progress of EMs.Methods The expression of MMP-9 and MVD in ectopic endometrial tissue of 45 cases with EMs and of 15 normal as the control was detected by immunohistochemical study.Results The expression of MMP-9 and the MVD were much higher in ectopic endometrial cells than those in the normal control; there existed no correlation between the expression of MMP-9 and that of MVD in ectopic endometriam (Pgt; 0.05) as well as in the control endometriam (Pgt; 0.05). Conclusions It may be related to the invasion of ectopic endometriam that the expression of MMP-9 and MVD increases in ectopic