Morphological myelodysplastic syndrome clinical significance in diagnosis.doc

 PAGE \* MERGEFORMAT 10 Morphological myelodysplastic syndrome clinical significance in diagnosis Of: Xu Hui Hui Chung Ping Chen Mu Qingyun [Abstract] Objective: To investigate the peripheral blood, bone marrow cells and bone marrow biopsy examination of morphological changes in myelodysplastic syndrome (MDS) diagnosis of clinical significance, in order to improve the diagnostic accuracy. Methods: The hospital in 2006 - 2008, 91 patients with clinical and hematological features were analyzed retrospectively. Results: 91 cases, peripheral blood pancytopenia in 42 cases (46.1%), 2 Department of cells decreased by 31 cases (34.1%), nucleated red blood cell classification shows 63 (69.2%), the original cells in 21 cases (23.1%), thrombocytopenia 67 cases (73.6%). Bone Marrow cytology: an extremely active to the active proliferation of 76 cases (83.5%), to reduce the proliferation of 15 cases (16.5%), 1, 2 RCMD, Department of 73 cases (80.2%). Bone marrow biopsy: 87 cases to the active proliferation of extremely active 69 cases (79.3%), reduced proliferation of 18 patients (20.7%), 3 tied with 72 different degrees of dysplasia cases (82.8%). Conclusion: MDS morphology complex, difficult to diagnose and lack of specificity of MDS peripheral examination provide the basis for the typing, bone marrow cells and bone marrow biopsy are two ways to check their own strengths, combined with more help accurate diagnosis of MDS. [Keywords:] myelodysplastic syndrome; morphology; blood; bone marrow examination; bone marrow biopsy Myelodysplastic syndrome (myelodysplasticsyndrome, MDS) is a group derived from hematopoietic stem cells to blood cell dysplasia, high-risk characteristics of the acute leukemia refractory into the cytoplasm of blood, the amount of abnormal heterogeneous disease [1]. morphological characteristics of the various types of abnormal blood cell morphology as the main features of the peripheral blood usually presents a series or two departments or