Nerve growth factor and endometriosis-related dysmenorrhea study.doc

 PAGE \* MERGEFORMAT 10 Nerve growth factor and endometriosis-related dysmenorrhea study Abstract] Objective To study the nerve growth factor (NGF in patients with endometriosis in the expression of ectopic endometrial tissue and the relationship with dysmenorrhea. Methods Immunohistochemical staining of nerve growth factor NGF differentiation in 28 cases of endometrial Bit disease and 26 cases of ectopic endometrium in normal endometrium, the expression of nerve growth factor NGF and EMs correlation of nerve growth factor NGF dysmenorrhea and endometriosis. Results of nerve growth factor NGF in endometriotic significantly higher than in normal endometrium, was statistically significant. moderate to severe pain group than in the increased expression of mild pain group. Conclusion endometriosis in a high expression of NGF ectopic endometrium, especially in severe pain group, suggesting that NGF dysmenorrhea and endometriosis are related. [Keywords:] endometriosis, nerve growth factor, immunohistochemistry, and the pain Correlation between nerve growth factor NGF and pain in patients with endometriosis GAO Hui, ZHANG Zhen.Departmont of Ostetrics and Gynecolegy, People’s Hospital of Linyi, Linyi 276000, China [Abstract] Objective To ivestigate the expression of nerve growth factor NGF in patients with endometriosis with and without pain.Methods Immunohistochemical methods were used to identify the expression of NGF in endometriotic (n = 28endometrium and nomal endometrium (n = 26.Results Increased expression of NGF in endometriotic was found as compared with nomal endometrium (P lt;0.05Conclusion Our results suggest that NGF were overexpressed in endometriotic tissues, NGF could be involved in the development of endometriotic lessions.NGF may be relevant to the pathogenesis of endometriosis with pain. [Keywords:] endometriosis; nerve growth factor; immunohistochemistry, pain Endometriosis is a common disease of women of childbearing age, frequent