Omeprazole mosapride treatment of reflux esophagitis in 50 Cases.docVIP

 PAGE \* MERGEFORMAT 7 Omeprazole mosapride treatment of reflux esophagitis in 50 Cases [Abstract] Objective To observe the omeprazole mosapride treatment of reflux esophagitis patients. Methods 50 patients with reflux esophagitis were randomly divided into 2 groups 25 patients: treatment group: Ogilvy amp; Mather pull-yl 20mg, once daily oral administration, mosapride 5 mg, 3 times a day orally, the control group: mosapride 5 mg, 3 times a day orally. Both groups were observed after 4 weeks of treatment efficiency and clinically significant efficient. the treatment group showed significantly higher efficiency and efficiency (P lt;0.05. Conclusions Omeprazole mosapride treatment of reflux esophagitis better efficacy than the single drug. [Keywords:] mosapride omeprazole reflux esophagitis Reflux esophagitis is an intractable digestive diseases, due to excessive stomach, duodenal contents into the esophagus caused by anti-acid reflux, difficulty swallowing and other symptoms, and lead to esophageal mucosal erosion, ulcers and other diseases, symptoms or tissue damage caused by the clinical is not uncommon. It is reported that reflux esophagitis gastroesophageal reflux disease accounts for about 48% to 79% [1]. reflux esophagitis patients as the main driving force obstacles mosapride in the digestive tract prokinetic agent, can selectively act on neurons in the gastrointestinal smooth muscle 5-HT 4 (5 HT4 receptors, cholinergic gastrointestinal tract through the middle of excitatory neurons and myenteric plexus of 5 HT4 receptor, to promote the release of acetylcholine, thereby enhancing the digestive tract (stomach and intestinal motility, gastrointestinal motility is a novel full of drug. We apply mosapride combined with proton pump inhibitors omeprazole treatment of reflux esophagitis, 50 patients achieved satisfactory results, are as follows. 1 Materials and Methods 1.1 General information select from March 2005 to June 2008 due to reflux esoph