Pathogenesis and treatment of attention deficit hyperactivity disorder.doc

 PAGE \* MERGEFORMAT 9 Pathogenesis and treatment of attention deficit hyperactivity disorder Children with attention deficit hyperactivity disorder (attention defect hyperactivity disorder, ADHD) referred to as hyperactivity, attention mainly obvious disorientation, and note that the duration was short, hyperactivity, impulsive behavior associated with learning difficulties and conduct disorder. At present the international community to be divided into three main types of ADHD: (1) attention-deficient; (2) hyperactive - impulsive type; (3) has the two characteristics of a hybrid. Children have a higher prevalence, China reported that ADHD was 1.3% ~ 13.4%, male to female ratio of 4.9:1 [1], which not only affects the children in school and family life, and could easily lead to learning difficulties, behavioral problems, some children continue to life. To this end the deepening study of the pathogenesis of ADHD in order to carry out effective treatment is very important, clinicians and education researchers analyzed and discussed in many ways, the development process at home and abroad will now be summed up as follows. 1 Pathogenesis Since the 1845 discovery of such behavior characteristics of children described to 1949 with brain damage as an important cause for the named minor brain damage syndrome in recent years, the organization finally established as the WHO hyperkinetic syndrome [2]. Many scholars study the etiology of many factors to explain its pathogenesis, genetic factors are more consensus study found that children with D4R gene polymorphism, and the pathogenesis of ADHD, it is mainly distributed in the frontal lobe, which prompts the abnormal function of the frontal DA neurons the lower trigger attention disorder. Molecular biology of dopamine metabolism or sensitivity increased, which is why it is taking the profits available to control symptoms after Lin [3]. Other studies are mostly concentrated in the hypothalamus, reticular activating syste