Patients with acute coronary syndrome tumor necrosis factor levels and the relationship between coronary plaque morphology.doc

 PAGE \* MERGEFORMAT 8 Patients with acute coronary syndrome tumor necrosis factor levels and the relationship between coronary plaque morphology [Abstract] Objective To investigate serum levels of tumor necrosis factor in patients with coronary heart disease @ (TNF @ level and the relationship between coronary artery plaque morphology and plaque rupture causes. Methods 109 patients hospitalized for coronary angiography were divided according to the clinical diagnosis of the control group and acute coronary syndrome (ACS group. and then by 64-slice spiral CT examination based on plaque morphology into normal control group, -type, type, type of plaque. For those who were included in the serum TNF @ detect and control analysis . Results ACS group , type, type of serum levels of TNF @ plaque group was significantly higher than normal coronary group (P lt;0.01), -type plaque TNF @ serum levels were significantly higher than that of type , type of spot block group (P lt;0.01), and -type plaque type group compared to the level of serum TNF @ has significantly increased. Conclusion increased levels of serum TNF @ is a risk factor for ACS, and its level can be used as an indicator to determine the severity of ACS one, suggesting that local inflammatory reaction leading to coronary plaque rupture is an important reason. [Key Words] multi-spiral computed tomography, coronary artery, tumor necrosis factor-@, plaque morphology Acute coronary syndrome (ACS) is one of the most common heart disease. Serum tumor necrosis factor @ (TNF @ inflammation as a sensitive indicator of the level and incidence of ACS, development and prognosis (1) For a long time, selective coronary angiography (coronary angiography, CAG) is a diagnosis of coronary heart disease remains the “gold standard”, but it is invasive examination. multislice spiral CT (MSCT) the emergence of a great impetus to the non-invasive coronary imaging technology (2). In this study, ACS patients by observi