Periconceptional birth defects in Shanxi rural case-control analysis of factors.docVIP

 PAGE \* MERGEFORMAT 12 Periconceptional birth defects in Shanxi rural case-control analysis of factors Of: Baiyun Zhang Hong Zhao Guoxing Ping Wang Yu Wang Huimei [Abstract] Objective To study birth defects in Shanxi Province Periconceptional factors, provide the basis for developing preventive measures. Methods to January 2006 ~ December 2008 6 months of birth defects in Shanxi County high incidence of birth defects in 492 cases of group of mothers of children the same period, 492 mothers of children with normal control group, type 4 49 periconceptional factors univariate analysis. the single factor analysis of 22 significant risk factors for the introduction of multiple unconditional logistic regression. Results previous birth defects children, immediate family child birth defects, pregnancy with fever, spontaneous abortion, pregnancy and child birth defects exposure to pets is a risk factor, the relative risk (OR) and 95% confidence interval (CI) were 744.94 (102.14 ~ 5 432.97), 8.81 (2.34 ~ 33.17), 2.38 (1.14 ~ 4.95), 2.29 (1.08 to 4.86), 1.73 (1.28 to 2.35); culture, high level of pregnancy are mostly carnivorous protective factor, OR (95% CI) 0.61 (0.44 ~ 0.83) and 0.59 (0.42 ~ 0.84). Conclusion strengthen Periconceptional health and reduce exposure to risk factors, is to reduce the incidence of birth defects in an important measure. [Keywords:] birth defect; Periconceptional; factors; logistic regression analysis [Abstract] Objective To explore risk factors for birth defects in rural areas of Shanxi Province, China. Methods Subjects included 492 fetuses or neonates with birth defects ascertained during Jan 2006 and Dec 2008 in six rural counties and 492 healthy neonates as controls randomly selected in similar residence during the same period. Risk factors of birth defects were analyzed using non conditional logistic regression. Results Multiple logistic regress analyses show that previous pregnancy affected by a birth defect (OR = 744.94,