Predict the progress of serum glutamate old value of ischemic stroke.doc

 PAGE \* MERGEFORMAT 8 Predict the progress of serum glutamate old value of ischemic stroke OF: Juan Zhang Yi Cui Wei Lu Gang Zhang Yu Xie [Abstract] Objective To investigate the progress of serum glutamate detection of the elderly predictive value of ischemic stroke. Methods aged 110 patients with ischemic stroke, according to the progress of the disease were divided into 2 groups: progressing ischemic cerebral infarction and 52 patients non-progress of 58 cases of ischemic stroke, serum glutamate levels were compared. Results progressive cerebral infarction in patients with serum glutamic acid levels higher than non-progressive group, the difference was statistically significant (P lt;0.01). Logistic Regression analysis showed that elevated levels of serum glutamate for older progressive ischemic stroke risk factors. Conclusions Elderly patients with ischemic stroke progression of serum glutamate levels and is closely related to elevated levels of glutamate in patients with more development for the progressive cerebral infarction. [Keywords:] ischemic stroke; progressive; glutamate Progressive cerebral infarction morbidity and mortality higher than the average cerebral infarction is an important prognostic one of the reasons is the difficulty the treatment of cerebrovascular disease, the exact mechanisms are not yet clear, there is no conclusive prognostic evaluation of .1964 , Olney proposed the term excitotoxicity (1), 1978 also proposed the disease in different neurons in excitotoxicity is a common pathway .1994 Lipton of Harvard University describes the system and its receptors of excitatory amino acids, carrier, calcium blockers and channel opening. excitatory neurotransmitter glutamate, as in the progression of cerebral infarction has important value. This study aimed to investigate the progress of serum glutamate detection of ischemic cerebral infarction forecast value. 1 Materials and Methods 1.1 Case Selection Select from Februar