Preparation Method of emodin.doc

 PAGE \* MERGEFORMAT 6 Preparation Method of emodin [Keywords:] Rheum palmatum;,, emodin;,, preparation method Abstract: Objective To search for emodin and efficient preparation method. Hydrolysis of anthraquinone glycosides method first and then use the pH gradient extraction separation, the final column chromatography. The results obtained by the spectral identification of the crystallization of emodin. Conclusion This method is the better of emodin in rhubarb preparation methods. Keywords:: Rheum palmatum; emodin; Preparation Study on the Preparation Method of Emodin Abstract: ObjectiveTo select efficient method for preparing emodin.MethodsHydrolyze the anthraquinone glycoside first and then separate them by PH gradient extraction, and purify emodin by chromatography at last.ResultsThe crystal was determined as emodin by means of spectra.ConclusionThis is a good method to produce pure emodin from R.palmatum. Keywords:: R. Palmatum; Emodin; Preparation Emodin is Polygonum Rheum palmatum Rheum palmatum L., tanguticum R.tanguticum such as medicinal herbs, one of the main active ingredient in recent years, it was discovered that emodin could inhibit tumor cell proliferation and induce apoptosis [1 ~ 3] , anti-inflammatory [4], anti-fibrosis [5], smooth muscle contraction [6] and so on effect on the increasing emphasis on the study of emodin and in-depth. However, we found that as the main source of emodin in rhubarb in addition to other well Chrysophanol emodin, rhein, emodin and aloe-emodin, and these ingredients in the herbal medicine mainly in the form of glycosides. Many researchers have received emodin purity of the samples is not enough, which will impact on the results of their research. This paper describes a medicine from Rheum palmatum Preparation of emodin method. 1 Equipment The melting point with the binocular microscope, as the micro-melting point tester (not corrected) measured with the Perkin-Elemer983 infrared IR Spectrometer (KBr tab