Pulse of Health Preparation of microcapsule suspension.doc

 PAGE \* MERGEFORMAT 9 Pulse of Health Preparation of microcapsule suspension [Abstract] Objective To study pulse microcapsule suspension of the preparation and quality evaluation. Methods filter orthogonal design optimal extraction process and microencapsulation technique, using thin-layer chromatography (TLC) method and high performance liquid chromatography (HPLC) method for identification and determination. Results microcapsule entrapment efficiency was 99.3%, capsule-shaped for the class round, microcapsule dissolution rate of 0.714 mg / min, identifying such compliance. Conclusion The preparation process is stable and reliable, and broken capsule method is effective. [Keywords:] microcapsules; ShengmaiYin; sodium alginate; Encapsulation Technology Abstract: ObjectiveTo study on the preparation of Shenmai aqueous capsule suspension and quality evaluation.MethodsThe best extraction and preparation technology was optimized by the orthogonal design, the methods of TLC and HPLC were used for the identification and content determination. ResultsThe entrapment efficiency was 99.3% , its shape was similar with circuit; the speed of dissolute microcapsules was 0.714 mg / min.ConclusionThe system is reliable, the method of the broken pouch is effective. Keywords:: Microcapsules; Shengmaiyin; Sodium alginate; Encapsulation Shengmaiyin is a well-known traditional Chinese medicine prescriptions, from red ginseng, Schisandra, Ophiopogon japonicus composed of three Chinese herbal medicines, has Yiqi Fumai, Sheng Jin antiperspirant efficacy in clinical used for the treatment of cardiovascular disease [1]. Now Yousheng pulse injection production, but production process complicated, easy to produce irritation and hemolysis and other issues have limited the use of the product. After the microencapsulation of drugs precisely to solve and avoid these problems, so that curing the liquid material, played the purpose of targeted drug delivery [2]. To facilitate the clinical